Dermal fillers are the better treatment option for more established and deep-set wrinkles. The plastic surgeon injects the fillers into areas of the face that have experienced fat loss and therefore have more of a sunken appearance. Patients can also opt for dermal fillers to add fullness, such as creating higher cheekbones or a cleft in the nose or chin. Most dermal fillers act as a sponge by absorbing water and plumping up the area where the doctor made the injection. Other fillers prompt the body to produce more collagen on its own.